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亚博app医学部吕德生教授团队和化学院张平玉老师合作在国际顶级学术期刊发表文章

来源: 发布时间: 2019-12-31 17:17 点击数: Views

亚博appjinri,yixuebulvdeshengjiaoshoutuanduihehuaxueyuanzhangpingyulaoshihezuozaiguojidingjixueshuqikan《angewandte chemie-international edition》(jcr1qutop,yingxiangyinzi: 12.959)fabiaotiwei《sulfur-coordinated organoiridium(iii) complexes exert anti-breast cancer activity via inhibiting wnt/β-catenin signaling》dewenzhang。zheipianwenzhangdesuoyougongzuojunzaiyaboappwancheng,yixuebusunqijiangshishizheipianwenzhangdediyizuozhe,lvdeshengjiaoshouhezhangpingyuzhulijiaoshouweigongtongtongxunzuozhe,yaboappweidiyiwanchengdanwei。

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图1.A.金属铱配合物B.含硫金属铱配合物能够通过靶向作用于Wnt/β-catenin信号通路的Wnt共受体LRP6对乳腺癌的发生发展及乳腺癌干性产生抑制作用

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2.与传统的金属药物顺铂相比含硫金属铱配合物能够显著抑制乳腺癌的肺部转移

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